| 2022-03-12 13:00:00March 12, 2022 | St George-Illawarra Dragons — Parramatta Eels | 6 - 34 | Knock On Effect NSW Cup | Kellyville Park | 1 |
| 2022-03-12 15:00:00March 12, 2022 | Newtown Jets — Canberra Raiders | 36 - 22 | Knock On Effect NSW Cup | Henson Park | 1 |
| 2022-03-12 15:00:00March 12, 2022 | South Sydney Rabbitohs — Canterbury-Bankstown Bulldogs | 16 - 24 | Knock On Effect NSW Cup | Belmore Sports Ground | 1 |
| 2022-03-12 15:00:00March 12, 2022 | Blacktown Sea Eagles — Penrith Panthers | 4 - 24 | Knock On Effect NSW Cup | BlueBet Stadium | 1 |
| 2022-03-13 10:30:00March 13, 2022 | Wests Magpies — Mounties | 16 - 20 | Knock On Effect NSW Cup | Kirkham Oval | 1 |
| 2022-03-13 14:00:00March 13, 2022 | Newcastle Knights — North Sydney Bears | 24 - 36 | Knock On Effect NSW Cup | Cessnock Sports Ground | 1 |
| 2022-03-19 15:10:00March 19, 2022 | St George-Illawarra Dragons — Penrith Panthers | 6 - 52 | Knock On Effect NSW Cup | BlueBet Stadium | 2 |
| 2022-03-20 12:45:00March 20, 2022 | Parramatta Eels — Newtown Jets | 24 - 28 | Knock On Effect NSW Cup | Kellyville Park | 2 |
| 2022-03-20 15:00:00March 20, 2022 | Mounties — South Sydney Rabbitohs | 18 - 32 | Knock On Effect NSW Cup | Aubrey Keech Reserve | 2 |
| 2022-03-20 16:00:00March 20, 2022 | Canterbury-Bankstown Bulldogs — Canberra Raiders | 48 - 12 | Knock On Effect NSW Cup | Accor Stadium | 2 |
| 2022-03-21 16:30:00March 21, 2022 | Newcastle Knights — Wests Magpies | 30 - 4 | Knock On Effect NSW Cup | Morry Breen Oval | 2 |
| 2022-03-25 17:45:00March 25, 2022 | South Sydney Rabbitohs — North Sydney Bears | 16 - 24 | Knock On Effect NSW Cup | Accor Stadium | 3 |
| 2022-03-26 14:15:00March 26, 2022 | St George-Illawarra Dragons — Newtown Jets | 10 - 50 | Knock On Effect NSW Cup | Kirkham Oval | 3 |
| 2022-03-26 17:15:00March 26, 2022 | Canberra Raiders — Wests Magpies | 47 - 24 | Knock On Effect NSW Cup | GIO Stadium | 3 |
| 2022-03-27 14:45:00March 27, 2022 | Penrith Panthers — Newcastle Knights | 40 - 10 | Knock On Effect NSW Cup | BlueBet Stadium | 3 |
| 2022-03-27 17:00:00March 27, 2022 | Mounties — Parramatta Eels | 12 - 18 | Knock On Effect NSW Cup | Aubrey Keech Reserve | 3 |
| 2022-03-28 19:00:00March 28, 2022 | Blacktown Sea Eagles — Canterbury-Bankstown Bulldogs | 0 - 30 | Knock On Effect NSW Cup | HE Laybutt | 3 |
| 2022-04-01 17:50:00April 1, 2022 | Penrith Panthers — South Sydney Rabbitohs | 18 - 20 | Knock On Effect NSW Cup | BlueBet Stadium | 4 |
| 2022-04-02 12:00:00April 2, 2022 | Mounties — Canterbury-Bankstown Bulldogs | 18 - 28 | Knock On Effect NSW Cup | Aubrey Keech Reserve | 4 |
| 2022-04-02 12:40:00April 2, 2022 | Newtown Jets — Newcastle Knights | 18 - 16 | Knock On Effect NSW Cup | Leichhardt Oval | 4 |
| 2022-04-03 15:00:00April 3, 2022 | Blacktown Sea Eagles — Canberra Raiders | 18 - 26 | Knock On Effect NSW Cup | HE Laybutt | 4 |
| 2022-04-03 15:50:00April 3, 2022 | Parramatta Eels — St George-Illawarra Dragons | 44 - 12 | Knock On Effect NSW Cup | CommBank Stadium | 4 |
| 2022-04-03 20:00:00April 3, 2022 | Wests Magpies — North Sydney Bears | 18 - 28 | Knock On Effect NSW Cup | Leichhardt Oval | 4 |
| 2022-04-09 12:40:00April 9, 2022 | Canberra Raiders — Mounties | 30 - 16 | Knock On Effect NSW Cup | McDonalds Stadium, Wagga | 5 |
| 2022-04-09 15:00:00April 9, 2022 | Newtown Jets — Wests Magpies | 40 - 10 | Knock On Effect NSW Cup | Henson Park | 5 |
| 2022-04-09 15:05:00April 9, 2022 | South Sydney Rabbitohs — St George-Illawarra Dragons | 26 - 30 | Knock On Effect NSW Cup | Accor Stadium | 5 |
| 2022-04-09 17:00:00April 9, 2022 | North Sydney Bears — Parramatta Eels | 30 - 16 | Knock On Effect NSW Cup | North Sydney Oval | 5 |
| 2022-04-10 12:30:00April 10, 2022 | Canterbury-Bankstown Bulldogs — Penrith Panthers | 16 - 30 | Knock On Effect NSW Cup | Belmore Sports Ground | 5 |
| 2022-04-10 13:30:00April 10, 2022 | Newcastle Knights — Blacktown Sea Eagles | 14 - 24 | Knock On Effect NSW Cup | Newcastle No.2 Sports Ground | 5 |
| 2022-04-15 13:40:00April 15, 2022 | South Sydney Rabbitohs — Newtown Jets | 32 - 10 | Knock On Effect NSW Cup | Accor Stadium | 6 |
| 2022-04-16 13:00:00April 16, 2022 | Canterbury-Bankstown Bulldogs — Newcastle Knights | 24 - 34 | Knock On Effect NSW Cup | Belmore Sports Ground | 6 |
| 2022-04-16 15:00:00April 16, 2022 | Mounties — Penrith Panthers | 16 - 42 | Knock On Effect NSW Cup | Belmore Sports Ground | 6 |
| 2022-04-16 16:00:00April 16, 2022 | North Sydney Bears — Canberra Raiders | 28 - 20 | Knock On Effect NSW Cup | North Sydney Oval | 6 |
| 2022-04-17 13:40:00April 17, 2022 | St George-Illawarra Dragons — Blacktown Sea Eagles | 42 - 4 | Knock On Effect NSW Cup | WIN Stadium | 6 |
| 2022-04-18 13:35:00April 18, 2022 | Parramatta Eels — Wests Magpies | 40 - 10 | Knock On Effect NSW Cup | CommBank Stadium | 6 |
| 2022-04-23 15:00:00April 23, 2022 | Newtown Jets — Blacktown Sea Eagles | 34 - 16 | Knock On Effect NSW Cup | Henson Park | 7 |
| 2022-04-24 11:30:00April 24, 2022 | Newcastle Knights — Parramatta Eels | 8 - 26 | Knock On Effect NSW Cup | McDonald Jones Stadium | 7 |
| 2022-04-24 13:00:00April 24, 2022 | Canterbury-Bankstown Bulldogs — Mounties | 18 - 10 | Knock On Effect NSW Cup | Belmore Sports Ground | 7 |
| 2022-04-24 13:45:00April 24, 2022 | Penrith Panthers — Canberra Raiders | 44 - 12 | Knock On Effect NSW Cup | BlueBet Stadium | 7 |
| 2022-04-24 14:00:00April 24, 2022 | North Sydney Bears — St George-Illawarra Dragons | 14 - 30 | Knock On Effect NSW Cup | North Sydney Oval | 7 |
| 2022-04-24 15:00:00April 24, 2022 | Wests Magpies — South Sydney Rabbitohs | 4 - 34 | Knock On Effect NSW Cup | Lidcombe Oval | 7 |
| 2022-04-30 12:40:00April 30, 2022 | Canterbury-Bankstown Bulldogs — North Sydney Bears | 12 - 18 | Knock On Effect NSW Cup | Accor Stadium | 8 |
| 2022-04-30 15:00:00April 30, 2022 | South Sydney Rabbitohs — Blacktown Sea Eagles | 26 - 12 | Knock On Effect NSW Cup | Redfern Oval | 8 |
| 2022-04-30 15:00:00April 30, 2022 | Penrith Panthers — Newtown Jets | 26 - 12 | Knock On Effect NSW Cup | St Marys Leagues Club | 8 |
| 2022-05-01 11:30:00May 1, 2022 | Newcastle Knights — Mounties | 34 - 22 | Knock On Effect NSW Cup | McDonald Jones Stadium | 8 |
| 2022-05-01 13:40:00May 1, 2022 | St George-Illawarra Dragons — Wests Magpies | 46 - 16 | Knock On Effect NSW Cup | WIN Stadium | 8 |
| 2022-05-01 15:00:00May 1, 2022 | Parramatta Eels — Canberra Raiders | 4 - 28 | Knock On Effect NSW Cup | Kellyville Park | 8 |
| 2022-05-06 17:40:00May 6, 2022 | Penrith Panthers — Parramatta Eels | 25 - 8 | Knock On Effect NSW Cup | BlueBet Stadium | 9 |
| 2022-05-07 12:40:00May 7, 2022 | Blacktown Sea Eagles — Wests Magpies | 26 - 30 | Knock On Effect NSW Cup | 4 Pines Park | 9 |
| 2022-05-07 13:00:00May 7, 2022 | St George-Illawarra Dragons — Canterbury-Bankstown Bulldogs | 6 - 26 | Knock On Effect NSW Cup | Collegians Sporting Complex | 9 |
| 2022-05-07 15:00:00May 7, 2022 | South Sydney Rabbitohs — Newcastle Knights | 37 - 14 | Knock On Effect NSW Cup | Redfern Oval | 9 |
| 2022-05-08 14:00:00May 8, 2022 | North Sydney Bears — Newtown Jets | 28 - 40 | Knock On Effect NSW Cup | North Sydney Oval | 9 |
| 2022-05-14 12:10:00May 14, 2022 | North Sydney Bears — Blacktown Sea Eagles | 56 - 18 | Knock On Effect NSW Cup | North Sydney Oval | 2 |
| 2022-05-20 17:55:00May 20, 2022 | Parramatta Eels — Blacktown Sea Eagles | 24 - 6 | Knock On Effect NSW Cup | CommBank Stadium | 11 |
| 2022-05-20 19:00:00May 20, 2022 | North Sydney Bears — Penrith Panthers | 12 - 17 | Knock On Effect NSW Cup | North Sydney Oval | 11 |
| 2022-05-21 11:30:00May 21, 2022 | South Sydney Rabbitohs — Canberra Raiders | 10 - 41 | Knock On Effect NSW Cup | Apex Oval | 11 |
| 2022-05-21 12:40:00May 21, 2022 | St George-Illawarra Dragons — Newcastle Knights | 20 - 27 | Knock On Effect NSW Cup | Netstrata Jubilee Stadium | 11 |
| 2022-05-21 15:00:00May 21, 2022 | Wests Magpies — Canterbury-Bankstown Bulldogs | 0 - 42 | Knock On Effect NSW Cup | Lidcombe Oval | 11 |
| 2022-05-21 15:00:00May 21, 2022 | Newtown Jets — Mounties | 26 - 12 | Knock On Effect NSW Cup | Henson Park | 11 |
| 2022-05-29 11:30:00May 29, 2022 | Canterbury-Bankstown Bulldogs — St George-Illawarra Dragons | 22 - 40 | Knock On Effect NSW Cup | Belmore Sports Ground | 12 |
| 2022-05-29 13:00:00May 29, 2022 | Wests Magpies — Newtown Jets | 21 - 21 | Knock On Effect NSW Cup | Lidcombe Oval | 12 |
| 2022-05-29 13:45:00May 29, 2022 | Canberra Raiders — Parramatta Eels | 28 - 28 | Knock On Effect NSW Cup | GIO Stadium | 12 |
| 2022-05-29 14:00:00May 29, 2022 | North Sydney Bears — South Sydney Rabbitohs | 32 - 24 | Knock On Effect NSW Cup | North Sydney Oval | 12 |
| 2022-05-29 14:00:00May 29, 2022 | Newcastle Knights — Penrith Panthers | 36 - 26 | Knock On Effect NSW Cup | Maitland Sports Ground | 12 |
| 2022-05-29 15:00:00May 29, 2022 | Mounties — Blacktown Sea Eagles | 40 - 10 | Knock On Effect NSW Cup | Aubrey Keech Reserve | 12 |
| 2022-06-03 17:40:00June 3, 2022 | Penrith Panthers — St George-Illawarra Dragons | 22 - 26 | Knock On Effect NSW Cup | BlueBet Stadium | 13 |
| 2022-06-03 19:00:00June 3, 2022 | Parramatta Eels — Mounties | 38 - 0 | Knock On Effect NSW Cup | Kellyville Park | 13 |
| 2022-06-04 14:15:00June 4, 2022 | Newcastle Knights — Canterbury-Bankstown Bulldogs | 16 - 20 | Knock On Effect NSW Cup | St Johns Oval | 13 |
| 2022-06-04 15:00:00June 4, 2022 | South Sydney Rabbitohs — Wests Magpies | 36 - 32 | Knock On Effect NSW Cup | Redfern Oval | 13 |
| 2022-06-04 17:05:00June 4, 2022 | Blacktown Sea Eagles — North Sydney Bears | 22 - 16 | Knock On Effect NSW Cup | 4 Pines Park | 13 |
| 2022-06-05 13:45:00June 5, 2022 | Canberra Raiders — Newtown Jets | 30 - 20 | Knock On Effect NSW Cup | GIO Stadium | 13 |
| 2022-06-11 13:00:00June 11, 2022 | St George-Illawarra Dragons — South Sydney Rabbitohs | 10 - 26 | Knock On Effect NSW Cup | Collegians Sporting Complex | 14 |
| 2022-06-11 15:00:00June 11, 2022 | Mounties — North Sydney Bears | 18 - 26 | Knock On Effect NSW Cup | Aubrey Keech Reserve | 14 |
| 2022-06-11 15:00:00June 11, 2022 | Canberra Raiders — Penrith Panthers | 34 - 12 | Knock On Effect NSW Cup | Belconnen Oval | 14 |
| 2022-06-12 11:30:00June 12, 2022 | Wests Magpies — Blacktown Sea Eagles | 40 - 30 | Knock On Effect NSW Cup | Campbelltown Stadium | 14 |
| 2022-06-12 13:05:00June 12, 2022 | Newcastle Knights — Newtown Jets | 12 - 38 | Knock On Effect NSW Cup | McDonald Jones Stadium | 14 |
| 2022-06-13 13:40:00June 13, 2022 | Canterbury-Bankstown Bulldogs — Parramatta Eels | 30 - 20 | Knock On Effect NSW Cup | Accor Stadium | 14 |
| 2022-06-18 15:00:00June 18, 2022 | Newtown Jets — Penrith Panthers | 6 - 26 | Knock On Effect NSW Cup | Henson Park | 15 |
| 2022-06-18 17:10:00June 18, 2022 | Parramatta Eels — North Sydney Bears | 20 - 31 | Knock On Effect NSW Cup | CommBank Stadium | 15 |
| 2022-06-19 11:30:00June 19, 2022 | Canberra Raiders — Newcastle Knights | 11:30:0011:30 | Knock On Effect NSW Cup | GIO Stadium | 15 |
| 2022-06-19 13:40:00June 19, 2022 | Canterbury-Bankstown Bulldogs — Wests Magpies | 48 - 12 | Knock On Effect NSW Cup | CommBank Stadium | 15 |
| 2022-06-19 15:00:00June 19, 2022 | Mounties — St George-Illawarra Dragons | 41 - 40 | Knock On Effect NSW Cup | Aubrey Keech Reserve | 15 |
| 2022-06-19 15:00:00June 19, 2022 | Blacktown Sea Eagles — South Sydney Rabbitohs | 12 - 38 | Knock On Effect NSW Cup | HE Laybutt | 15 |
| 2022-07-01 17:40:00July 1, 2022 | Penrith Panthers — North Sydney Bears | 24 - 20 | Knock On Effect NSW Cup | BlueBet Stadium | 16 |
| 2022-07-02 12:40:00July 2, 2022 | Canterbury-Bankstown Bulldogs — Newtown Jets | 16 - 28 | Knock On Effect NSW Cup | CommBank Stadium | 16 |
| 2022-07-02 15:00:00July 2, 2022 | Wests Magpies — Newcastle Knights | 18 - 12 | Knock On Effect NSW Cup | Campbelltown Stadium | 16 |
| 2022-07-02 17:10:00July 2, 2022 | South Sydney Rabbitohs — Parramatta Eels | 14 - 16 | Knock On Effect NSW Cup | Accor Stadium | 16 |
| 2022-07-03 13:40:00July 3, 2022 | St George-Illawarra Dragons — Canberra Raiders | 13:40:00Postponed | Knock On Effect NSW Cup | WIN Stadium | 16 |
| 2022-07-03 15:00:00July 3, 2022 | Blacktown Sea Eagles — Mounties | 10 - 20 | Knock On Effect NSW Cup | HE Laybutt | 16 |
| 2022-07-08 17:10:00July 8, 2022 | Newcastle Knights — South Sydney Rabbitohs | 26 - 14 | Knock On Effect NSW Cup | McDonald Jones Stadium | 17 |
| 2022-07-09 15:00:00July 9, 2022 | Penrith Panthers — Canterbury-Bankstown Bulldogs | 22 - 12 | Knock On Effect NSW Cup | BlueBet Stadium | 17 |
| 2022-07-09 15:00:00July 9, 2022 | Canberra Raiders — North Sydney Bears | 30 - 16 | Knock On Effect NSW Cup | Belconnen Oval | 17 |
| 2022-07-09 15:00:00July 9, 2022 | Mounties — Newtown Jets | 14 - 46 | Knock On Effect NSW Cup | Aubrey Keech Reserve | 17 |
| 2022-07-09 17:05:00July 9, 2022 | Wests Magpies — Parramatta Eels | 20 - 38 | Knock On Effect NSW Cup | Leichhardt Oval | 17 |
| 2022-07-10 15:00:00July 10, 2022 | Blacktown Sea Eagles — St George-Illawarra Dragons | 16 - 34 | Knock On Effect NSW Cup | 4 Pines Park | 17 |
| 2022-07-16 12:40:00July 16, 2022 | Blacktown Sea Eagles — Newcastle Knights | 12 - 32 | Knock On Effect NSW Cup | 4 Pines Park | 18 |
| 2022-07-16 13:00:00July 16, 2022 | Wests Magpies — Penrith Panthers | 32 - 20 | Knock On Effect NSW Cup | Leichhardt Oval | 18 |
| 2022-07-17 13:00:00July 17, 2022 | Parramatta Eels — Newtown Jets | 10 - 30 | Knock On Effect NSW Cup | Henson Park | 18 |
| 2022-07-17 13:00:00July 17, 2022 | St George-Illawarra Dragons — North Sydney Bears | 28 - 28 | Knock On Effect NSW Cup | Collegians Sporting Complex | 18 |
| 2022-07-17 15:00:00July 17, 2022 | Mounties — Canberra Raiders | 20 - 18 | Knock On Effect NSW Cup | Aubrey Keech Reserve | 18 |
| 2022-07-17 16:00:00July 17, 2022 | Canterbury-Bankstown Bulldogs — South Sydney Rabbitohs | 20 - 10 | Knock On Effect NSW Cup | Accor Stadium | 18 |
| 2022-07-23 12:40:00July 23, 2022 | Canberra Raiders — Canterbury-Bankstown Bulldogs | 26 - 39 | Knock On Effect NSW Cup | GIO Stadium | 19 |
| 2022-07-23 14:00:00July 23, 2022 | Newcastle Knights — St George-Illawarra Dragons | 22 - 24 | Knock On Effect NSW Cup | St Johns Oval | 19 |
| 2022-07-23 15:00:00July 23, 2022 | Newtown Jets — North Sydney Bears | 20 - 14 | Knock On Effect NSW Cup | Henson Park | 19 |
| 2022-07-23 17:10:00July 23, 2022 | South Sydney Rabbitohs — Mounties | 30 - 0 | Knock On Effect NSW Cup | Accor Stadium | 19 |
| 2022-07-24 15:00:00July 24, 2022 | Penrith Panthers — Blacktown Sea Eagles | 48 - 6 | Knock On Effect NSW Cup | HE Laybutt | 19 |
| 2022-07-29 18:00:00July 29, 2022 | Parramatta Eels — Penrith Panthers | 24 - 25 | Knock On Effect NSW Cup | CommBank Stadium | 20 |
| 2022-07-30 12:40:00July 30, 2022 | Mounties — Wests Magpies | 36 - 24 | Knock On Effect NSW Cup | Campbelltown Stadium | 20 |
| 2022-07-30 15:00:00July 30, 2022 | Canberra Raiders — St George-Illawarra Dragons | 18 - 30 | Knock On Effect NSW Cup | Belconnen Oval | 20 |
| 2022-07-30 15:00:00July 30, 2022 | Newtown Jets — South Sydney Rabbitohs | 42 - 18 | Knock On Effect NSW Cup | Henson Park | 20 |
| 2022-08-06 12:40:00August 6, 2022 | Canberra Raiders — South Sydney Rabbitohs | 12 - 20 | Knock On Effect NSW Cup | GIO Stadium | 21 |
| 2022-08-06 13:00:00August 6, 2022 | Penrith Panthers — Wests Magpies | 56 - 6 | Knock On Effect NSW Cup | BlueBet Stadium | 21 |
| 2022-08-06 15:00:00August 6, 2022 | Newtown Jets — St George-Illawarra Dragons | 32 - 10 | Knock On Effect NSW Cup | Henson Park | 21 |
| 2022-08-07 14:00:00August 7, 2022 | North Sydney Bears — Canterbury-Bankstown Bulldogs | 30 - 20 | Knock On Effect NSW Cup | North Sydney Oval | 21 |
| 2022-08-07 15:00:00August 7, 2022 | Mounties — Newcastle Knights | 28 - 26 | Knock On Effect NSW Cup | Aubrey Keech Reserve | 21 |
| 2022-08-07 15:00:00August 7, 2022 | Blacktown Sea Eagles — Parramatta Eels | 12 - 30 | Knock On Effect NSW Cup | HE Laybutt | 21 |
| 2022-08-12 17:30:00August 12, 2022 | Parramatta Eels — South Sydney Rabbitohs | 32 - 10 | Knock On Effect NSW Cup | CommBank Stadium | 22 |
| 2022-08-13 12:40:00August 13, 2022 | Penrith Panthers — Mounties | 42 - 10 | Knock On Effect NSW Cup | BlueBet Stadium | 22 |
| 2022-08-14 14:00:00August 14, 2022 | Canterbury-Bankstown Bulldogs — Blacktown Sea Eagles | 38 - 12 | Knock On Effect NSW Cup | Belmore Sports Ground | 22 |
| 2022-08-14 14:00:00August 14, 2022 | Wests Magpies — Canberra Raiders | 22 - 26 | Knock On Effect NSW Cup | Leichhardt Oval | 22 |
| 2022-08-14 14:00:00August 14, 2022 | North Sydney Bears — Newcastle Knights | 60 - 4 | Knock On Effect NSW Cup | North Sydney Oval | 22 |
| 2022-08-18 17:25:00August 18, 2022 | South Sydney Rabbitohs — Penrith Panthers | 24 - 24 | Knock On Effect NSW Cup | Accor Stadium | 23 |
| 2022-08-20 11:00:00August 20, 2022 | Parramatta Eels — Canterbury-Bankstown Bulldogs | 16 - 19 | Knock On Effect NSW Cup | CommBank Stadium | 23 |
| 2022-08-20 15:15:00August 20, 2022 | Blacktown Sea Eagles — Newtown Jets | 8 - 50 | Knock On Effect NSW Cup | 4 Pines Park | 23 |
| 2022-08-21 11:00:00August 21, 2022 | St George-Illawarra Dragons — Mounties | 34 - 35 | Knock On Effect NSW Cup | Collegians Sporting Complex | 23 |
| 2022-08-21 13:30:00August 21, 2022 | Newcastle Knights — Canberra Raiders | 12 - 26 | Knock On Effect NSW Cup | McDonald Jones Stadium | 23 |
| 2022-08-21 14:00:00August 21, 2022 | North Sydney Bears — Wests Magpies | 24 - 20 | Knock On Effect NSW Cup | North Sydney Oval | 23 |
| 2022-08-26 19:00:00August 26, 2022 | Parramatta Eels — Newcastle Knights | 24 - 4 | Knock On Effect NSW Cup | Kellyville Park | 24 |
| 2022-08-27 11:00:00August 27, 2022 | Canberra Raiders — Blacktown Sea Eagles | 24 - 12 | Knock On Effect NSW Cup | GIO Stadium | 24 |
| 2022-08-27 15:00:00August 27, 2022 | Newtown Jets — Canterbury-Bankstown Bulldogs | 22 - 22 | Knock On Effect NSW Cup | Henson Park | 24 |
| 2022-08-28 14:00:00August 28, 2022 | North Sydney Bears — Mounties | 60 - 6 | Knock On Effect NSW Cup | North Sydney Oval | 24 |
| 2022-08-28 19:30:00August 28, 2022 | Wests Magpies — St George-Illawarra Dragons | 38 - 22 | Knock On Effect NSW Cup | Leichhardt Oval | 24 |
| 2022-09-03 15:10:50September 3, 2022 | Panthers — Bears | 22 - 14 | Knock On Effect NSW Cup | St Marys Leagues Club | Week1Finals |
| 2022-09-03 17:15:49September 3, 2022 | Bulldogs — Eels | 18 - 6 | Knock On Effect NSW Cup | St Marys Leagues Club | Week1Finals |
| 2022-09-10 13:00:43September 10, 2022 | Jets — Panthers | 18 - 28 | Knock On Effect NSW Cup | Netstrata Jubilee Stadium | Week2Finals |
| 2022-09-10 17:00:11September 10, 2022 | Bears — Bulldogs | 10 - 22 | Knock On Effect NSW Cup | Netstrata Jubilee Stadium | Week2Finals |
| 2022-09-17 15:10:43September 17, 2022 | Jets — Bulldogs | 26 - 28 | Knock On Effect NSW Cup | Leichhardt Oval | Week3Finals |
| 2022-09-25 15:00:52September 25, 2022 | Panthers — Bulldogs | 29 - 22 | Knock On Effect NSW Cup | CommBank Stadium | GrandFinal |
